ea0056gp207 | Pituitary Clinical | ECE2018
Gil Joan
, Blanco Alberto
, Serra Guillermo
, Salinas Isabel
, Webb Susan M
, Hostalot Cristina
, Obiols Gabriel
, Valassi Elena
, Roig Olga
, Sesmilo Gemma
, Villabona Carles
, Jorda Mireia
, Puig-Domingo Manel
Non-functioning pituitary adenomas (NFPA) are the most common pituitary tumours. They usually come to medical attention because of a mass effect and/or hypopituitarism. Tumour shrinkage during therapy with either dopamine agonists (DA) or somatostatin analogues (SSA) has been previously reported in some cases; however, response of NFPA to medical treatment is still poor and unpredictable. Our aim was to explore the molecular mechanisms underlying this lack of efficacy through ...